Osmolality testing is required to ensure that the final vaccine product is safe for administration. The osmolality must be within a physiological range to be introduced in human tissues. There is also evidence that injectable formulations with high osmolality may cause pain at the site of injection.
Vaccines are derived from a variety of sources, both living and synthetic, meaning a variety of bioproduction workflows are required. These workflows include some common use cases for osmolality testing such as cell culture monitoring, buffer media preparation, and final QC.
With the OsmoTECH® portfolio of osmometer you can always ensure product quality throughout every step of vaccine manufacturing.