The STUDIUS Powered Ecosystem incorporates critical data from Solentim VIPS™ single cell seeding, Cell Metric® clone verification and colony outgrowth monitoring and ICON™ cell IgG productivity assessments to provide a unique decision-making platform covering the CLD workflow from cell seeding to scaled-down mini-bioreactor studies, for example with the Ambr®. The data management STUDIUS™ provides the ability to automatically create high quality supporting documentation, reducing data analysis times, and enabling faster decision making.
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Components of the STUDIUS Powered Ecosystem
Solentim VIPS
Verified In-Situ Plate Seeding (VIPS) takes single cell cloning and image based clonality assurance to a whole new level of quality. The multi-tasking, compact instrument delivers a rock solid, ‘double-lock’ solution for regulatory submissions. Gentle seeding process ensures high cell viability, thus improved seeding efficiency, clonal outgrowth and unquestionable proof of monoclonality outgrowth. VIPS accelerates projects. High seeding efficiency for both 96 and 384 well plates and single round of cloning significantly reduces timelines and r enhanced overall productivity.
Solentim Cell Metric
Cell Metric is a high contrast imager designed for single cell imaging, identification and clonal outgrowth characterization. Cell Metric captures and records crucial evidence, whole well image of the single cell at day 0 and daily imaging thereafter, all wrapped up in a Clonality Report defining best practice for Master Cell Bank production. Available as a stand-alone single plate system, or with automated plate handling and a temperature-controlled environment for screening of up to 10 plates at the time (Cell Metric CLD). Cell Metric can be easily integrated into your current workflow thanks to compatibility with third party robotic systems.
Solentim ICON
Uniquely combines titer, viable cell count and accurate productivity data using low volume assays on a single reader, with the clonality and confluence data from Cell Metric and/or VIPS to track and rank clones automatically, rapidly and consistently from the cloning plate, through fed-batch suspension shaking cultures to shake flask and multi-parallel mini bio-reactors such as Ambr, regardless of the different formats used and without the risk of error.
Ambr® is a registered trademark of Sartorius AG
