Whether you work with monoclonal antibodies, bio-similars, viral vectors, bi-specifics, multi-specifics, or fusion-proteins, we deliver forward-thinking technologies that deliver time- and labor-saving advantages for therapeutic protein discovery and development while ensuring quality and productivity.
Our instruments streamline cell line development workflows – from single cell seeding, optimal clone selection and imaging, to bioprocessing osmometers that deliver valuable data for managing process and product quality, we bring together efficiency and quality to accelerate therapeutic protein development.
Our Solentim Ecosystem of cell line development products supports high cell growth and streamlines essential processes in your mAb workflow.
When it comes to process development and manufacturing of therapeutic proteins, what you don’t know can slow you down:
With our innovative osmometers, you can gain valuable data for managing process and product quality through a simple 90-second test.
Osmolality, the measurement of total solute concentration, is a reliable control specification and in-process parameter that can deliver information across the protein therapeutic process development and manufacturing workflow.
ELISA’s can provide very accurate and reliable results if conditions are right, but if conditions are incorrect, assays can fail or even produce false results. Liquid handling verification technology can help develop the test plan and protocol for diagnostic assays faster and with more confidence than manual methods.
Whether you are using a manual multichannel pipette or an automated liquid handler, you can use the MVS to assess mixing, washing, and reagent dispense steps, which can help you get to optimal conditions much faster, thus saving time, reagents, and reducing expenses.
Learn more about how our technologies bridge efficiency and quality to accelerate therapeutic protein development by checking out our educational resources below
Bioprocessing Case Study
Bioprocessing Case Study
Bioprocessing Case Study
Bioprocessing App Note
Bioprocessing App Note
Bioprocessing App Note
Get the best performance from your instruments from the people who designed and built them. We provide a range of services and service plans to meet the different needs of our customers.
Our certified Field Service Engineers provide on-site professional support for the installation, training, validation, and maintenance of your Advanced Instruments products.Learn more
The Artel MVS simplifies fluid verification of all automated liquid handlers and multichannel pipettes. The system is fast, calculates all plate and well statistics (Relative Inaccuracy, Coefficient of Variation, Standard Deviation and Mean) and it is simple to set up and use. For all of its capabilities and low-cost point...the MVS is one of the best value purchases I have ever made for my lab.
We had a demo of the [OsmoTECH PRO] instrument after seeing it at BPI East. The sales managers were prompt in setting up a lunch and learn. The instrument itself was very easy to run samples on and allowed for true load and walk away functionality. The sales managers were thorough professionals, waiting for our PO to go through and working with us to ensure we received the item within a week of ordering. It has the ability to run 20 samples at a time and is great value for the money spent.
The [Insti-reagents] product worked as expected and was very useful in outgrowing clones from a single cell to shaking cultures. Highly recommend.
The Artel MVS makes it so easy to do a monthly verification that the 96 channel CORE head on my Hamilton Vantage is dispensing the correct volumes. Doing the confirmation gravimetrically would be so time consuming, but using the Artel dyes and the MVS makes it something one person can do in a single morning. The software is easy to use, and the instrument has not had any maintenance issues.
This [OsmoTECH] instrument was a dream come true. The administrator can lock down features and dictate what users can and cannot do. Very easy to use and extremely reliable instrument.
The best part of the [OsmoTECH] instrument is it gives accurate and reproducible results for any solution and most importantly in less than a minute you have the results.
[The OsmoTECH] achieves high quality and reproducible results. Easy instrument to use and well-presented software.
[The OsmoTECH PRO] instrument is simple to operate with minimal consumables.
We use the PCS pipette calibration system. It has always been super reliable and accurate, and we have never had a single issue in the 8 years I have worked with it. The kits containing the solutions for the PCS are customizable, so you don't have to buy solutions you don't need. We do performance checks on our pipettes on a daily basis, so we could not live without it! It makes our jobs so much easier too!
The Artel PCS makes checking the pipetting proficiency of new hires quick and easy. It's also great for checking pipettes that may not be functioning properly.
The Artel MVS has been a huge help for our lab in validating volumes on new automated liquid handlers. Always gives consistent results, easy to use, software is extremely straightforward, and any time we have an issue, it's super easy to get help from the Artel team. Thank you!
The MVS system is extremely useful for periodic performance QC testing of high-throughput liquid handlers, high-throughput liquid handler calibration, and various liquid handler/single channel pipette tip type/lot QC. The MVS system requires minimal maintenance and MVS manager software is intuitive to use and flexible to set up various plate layouts to meet user’s need. The customer service is very responsive and helpful. They provide a notification for calibrator plate re-certification annually ...
The [Artel MVS] product is accurate and reliable. With the addition of the pre-owned models of MVS readers, it also becomes affordable. The expansion of the dye solutions to include MasterMix and Serum along with their original aqueous offering makes Artel a definitive liquid class setup solution. The FSE performing setup and the account manager were on-time, responsive, and supportive during install and (most importantly) afterwards.
The Artel application scientist is easy to work with, knowledgeable about interpreting test data and giving advice, and flexible to help onsite if needed. I would recommend the Artel MVS because it saves time and material cost. Most important is having a standard method to calibrate different pipettes and optimize liquid class on automated liquid handlers while managing the sources of variability systematically.
This [OsmoTECH PRO] osmometer is an accurate and convenient tool for the needs of our lab. Our lab works in the developmental stage of pharmaceuticals, and requires quick, precise bursts of osmolality checking for QC - and this instrument (with a load capacity of 20 samples) takes care of those needs. With developmental drugs, limited sample volume is often an issue - this instrument only needs 30uL (and takes ~90 seconds a measurement).
Osmolality measurements are easy and reliable with this [OsmoTECH PRO] instrument.
[The OsmoTECH PRO is] very easy to use for all technicians in a quality control lab. Small sample size. Friendly technicians that explained how to use the product very well.
[The OsmoTECH PRO is] very easy to use due to short analysis time and sample preparation.
[The OsmoTECH PRO is a] great system for multiple sample testing. Very straightforward and easy to use.
[The OsmoTECH XT is] easy to use, reliable and self-navigating options menu.
The [OsmoTECH] is highly effective and obtained results are of high quality. With this instrument I can develop my formulation for meeting the osmolality criteria for drug products.
[The OsmoTECH is] easy to use and robust piece of equipment that met all our user and regulatory requirements. The hardware is sleek, efficient and easy to use. The integrated software has built in data integrity controls and is thoroughly tested through validation test scripts / reports.
The Artel PCS fulfills our requirements on ISO compliant pipette calibration and testing. Results are reproducible and variance is lower than in manual process. Personnel is easily trained on the device. Process is faster than manual process.
The MVS system is fairly intuitive to use. Not only can we use this for our internal automated liquid handler volume verification, tip test and calibration work, we have been using the system to offer external volume verification service to our collaborators. The system is very durable without significant issues and easy to maintain. MVS reagent orders are always processed and delivered in a timely manner. Our regional specialist periodically checks in to ask if the system is working as expected.
The [Artel MVS] is easy to use, gives accurate and reliable results. It's a great way to quickly determine the functioning of the automation systems that we install and maintain.
Equipment was easy to set up and easy to use. The [OsmoTECH HT] runs reliably and is great to have for running many samples.
[The OsmoTECH PRO is an] excellent product and extremely efficient! Easy to clean and maintain. Excellent customer support and allows increased in-process testing capabilities.
The [OsmoTECH PRO] is very easy to use. Allows my lab to update a 20+ year old instrument, also from Advanced.
[The OsmoTECH XT is a] robust and versatile instrument that meets all of our osmolality needs!
[With the VIPS PRO], we can trace back the data to the single cell, select from our top 48 cell lines, and report all the information – our proof of monoclonality is already in there, and that’s really nice.
The Enhanced Clonality Reports easily generated by the VIPS/Cell Metric software allows us to track both cells and potential debris from first inception of the single cell in the well, to full-grown colonies enabling us to provide our customers with full traceability and audit trail of each cell line we produce for them with a single, well-crafted document.
The VIPS™ is unique, being the only single cell cloning system on the market that tracks a single cell’s arrival in the actual well with high resolution (z-stack) imaging and to support the subsequent daily whole well imaging provided by the Cell Metric.
The VIPS system allowed us to shave off a few months from our development timeline and select highly stable single clones for manufacturing purposes.
The VIPS™ system and software has helped our company to deliver a high-quality data-package that meets global regulatory standards...The ease of use and reliability of the VIPS freed up valuable time.
Once we brought [the Artel MVS] into the lab, we realized we could push to small volumes. We typically work beyond the liquid handler’s specifications, and we can do this because we have Artel to verify their performance.
The Artel MVS System has greatly improved our laboratory quality processes, not only streamlining instrument qualifications but accelerating verification and validations.
We rely on the MVS for verifications and liquid class development and optimization…
The [Artel MVS] simplified and streamlined our QC process…
The MVS system has been vital to our lab operations.
Cell Metric X had the best whole-well imaging capabilities and clonality reports and, when we demoed the instrument, we were convinced by the robustness of the system and very high image quality.
The Solentim ecosystem, [and Cell Metric X], allowed Wheeler to rapidly develop and launch a standardized cell line development service that is integrated with a scalable drug substance process.
In the beginning, you never know which kind of samples you’re going to test, and the [OsmoTECH XT] osmometer offers an amazing range of osmolality testing: from 0 to 4000 mOsm/kg H2O.
Osmolality testing is crucial for process development, analytical development and GMP testing. We need to meet the regulatory requirements [with the OsmoTECH XT] for the product to be released to the market or to be released to go to a patient.