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Three Things to Know About OsmoTECH® PRO

What Customers Value

“This osmometer is an accurate and convenient tool for the needs of our lab. Our lab works in the developmental stage of pharmaceuticals, and requires quick, precise bursts of osmolality checking for QC – and this instrument (with a load capacity of 20 samples) takes care of those needs. With developmental drugs, limited sample volume is often an issue – this instrument only needs 30µL (and takes ~90 seconds a measurement).”

- Sasha Sheptovitsky, Alexion Pharmaceuticals

Improving Titer, Quality and Efficiency of AAV Manufacturing and Production by Optimizing Osmolality

When speaking to process development scientists, it is clear the 3 main pain points within their manufacturing and production processes are: low yield, the quality of that yield, and the efficiency of their overall workflow.

Increasing the manufacturing capacity, improving the production yields and the improvement of the supply chain logistics, can make these therapies accessible to larger patient populations, all with hopefully a sustainable cost.

There is now clear evidence to show how the manipulation of this critical process parameter can improve overall outcomes. The study presented here, undertaken by Cell and Gene Therapy Catapult, provides preliminary evidence for impact on overall yield, and quality of the adeno-associated virus 1 (AAV) due to a timed osmolality shift with and without a feeding step.

Award Nominated Osmolality Testing

Instrument Features include:

  • 20- position sample turntable enables walk-away testing
  • Gold-standard testing method—freezing point depression—to accurately and precisely determine osmolality
  • Just a 30 μL sample volume is needed, facilitating sample-limited applications
  • Data integrity features support 21 CFR part 11, GMP and EU Annex 11 compliance

The Award Winning OsmoTECH® Portfolio

OsmoTECH® HT Automated Micro-Osmometer

Only Plate-Based Osmometer for High-Throughput Bioprocessing Labs

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OsmoTECH® PRO Multi-Sample Micro-Osmometer

Designed to meet the high sample throughput, regulatory compliance, and data management needs of busy bioprocessing and biomanufacturing labs.

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OsmoTECH® XT Single-Sample Micro-Osmometer

Best-in-class osmolality performance, designed with you in mind​.

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