Three physicians partnered with Advanced Instruments to share their experiences regarding the utility of osmolality testing and the implications of this critical test on quality and cost of patient care.

Dr. Neville R. Dossabhoy is a consulting nephrologist in Louisiana.

Dr. David Schindler is an attending physician in the Department of Emergency Medicine at Cornwall Community Hospital in Cornwall Ontario, Canada and Massena Memorial Hospital in Massena, New York.

Dr. Namrata Sharma Goel is a Nephrologist at the Kidney Health Center in Houston, Texas.


Osmolality is a fundamental measurement of the total solute concentration of body fluids, including but not limited to, whole blood, serum, plasma, urine, and stool. It is a valuable clinical tool in the diagnosis and treatment of patients.

Osmolality is a quick and effective test to help:

  • Evaluate the body’s water balance and its ability to produce and concentrate urine
  • Investigate low sodium levels (hyponatremia)
  • Detect the presence of toxins in the body
  • Monitor the electrolyte balance of patients receiving osmotically active drug therapies (e.g. mannitol used to treat cerebral edema).

It can also help monitor the effectiveness of a treatment or a condition found to be adversely affecting a person’s osmolality.

I’d like to start a conversation about osmolality

*The views and opinions expressed in the application notes are those of the authors and are intended for educational purposes.