The Osmo1® Single-Sample Micro-Osmometer is the replacement for the Model 3250 Single-Sample Osmometer which was discontinued in 2020. The Osmo1 provides additional benefits over the Model 3250 including but not limited to a touchscreen display for ease-of-use, integrated barcode scanning, a small 20 µL sample size and the elimination of heat transfer fluid. This paper summarizes a study comparing the performance of the Osmo1 and Model 3250 osmometers. In the study, the Osmo1 exhibited no significant performance difference compared to the Model 3250 and met all acceptance criteria for linearity, precision and accuracy.
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