- Automated decision making platform
- Integration across the Solentim portfolio
- Sample Tracking
- Automatic Triaging
- Immediate Triaging
- Error free Triaging
- Clonality Reporting
The STUDIUS powered ecosystem from Solentim provides a more consistent cell line development workflow for scientists creating biotherapeutic Master Cell Banks, enabling faster and more confident decision-making.
STUDIUS incorporates critical data from Solentim VIPS® PRO single cell seeding, Cell Metric® clone verification and colony outgrowth monitoring and ICON™ cell IgG productivity assessments. This provides a unique decision-making platform for the cell line development workflow from static cloning plates, through different suspension cell culturing formats and into multi-parallel high throughput mini-bioreactors such as Ambr®.
STUDIUS provides consistency across the cell line development workflow via secure sample/clone tracking and a common database and eliminates cumbersome and error prone comparison of results in various formats from multiple instruments from different suppliers.
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HISTORYTREE graphically represents a cell’s journey through cell line development, independent of sample formats. From seeding, through growth, productivity assays, ranking and selection, colored nodes represent time points in the cell’s journey offering easy access to critical data and an audit trail. For automated liquid handlers, STUDIUS communicates source and destination locations to the robot ensuring consistent sample tracking.
The current paradigm in cell line development involves comparison and cross referencing of excel spreadsheets containing for example, clonal outgrowth and productivity results. This tedious process increases the risk of error and reduces confidence in the overall clone selection process. STUDIUS manages results from Solentim’s cell line development instrument portfolio, thus eliminating time consuming and error-prone visual comparison of data in different formats.
In the STUDIUS ecosystem, raw data results from all instruments go directly and securely without external manipulation into a single common database for ultimate data integrity. Regardless of using this data for processing and reporting by the individual user, the raw data is always maintained.
In the STUDIUS powered ecosystem, ranking and decision-making are performed automatically and instantly, according to user defined parameters. A process that previously took hours or days repetitively comparing results in a variety of formats is performed by the software to deliver ranking and selection of clones in minutes according to user defined parameters such as clonality, confluence and titer.
Ambr®  is a registered trademark of Sartorius AG
STUDIUS spans across the cell line development workflow with features such as sample tracking, audit trails and multi-level password protected user access providing a toolkit for easy compliance with 21 CFR part 11, Annex 11 and other guidelines. Reporting is easy with automatically created reports of clonality.
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