Cell Metric Whole Well Imager | Advanced Instruments
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Solentim Cell Metric®

Highlighted Features
  • Right up to the edge imaging
  • Clarity in purpose​
  • Automated confluence determination
  • Always in focus
  • Fluorescence imaging for rare event detection
  • An audit of cell history

Solentim Cell Metric®

The Trusted Standard for Clonal Assurance

Cell Metric is a high contrast imager designed for single cell imaging, identification and clonal outgrowth characterization.

Key Whole-Well Evidence

Cell Metric captures and records crucial evidence, whole well image of the single cell at day 0 and daily imaging thereafter, all wrapped up in a clonality report defining best practice for Master Cell Bank production.

Available as a stand-alone single plate system, or with automated plate handling within a temperature-controlled environment from Cell Metric CLD or downstream third-party robotic integration. Cell Metric also integrates with your VIPS™ system via Data Sync system for enhanced laboratory workflows.

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“The Cell Metric was designed with the end user in mind. Set-up and use are easy and the ability to generate a clonality report at the end of a project is fantastic. I would highly recommend taking a very close look at the Cell Metric before adding any imaging system to a CLD workflow.”Ray Davis, RuffLife Consulting

“By adopting VIPS and Cell Metric, the CLD team can cut our timelines for transfection to Ambr15® from 6 months down to 10-13 weeks.”Jolanda Gerritsen, Technology Expert, Cell Line Development, Genmab

Overview

Evidence that it started as a single cell

Daily Whole Well Imaging

Cell Metric combines high quality images with data continuity, providing daily imaging with recorded evidence of single-cell to clonal growth.

High Resolution Images

Specialized, high quality images enable the user to observe and clearly annotate single cells. Single cells are discriminated from doublets and wells not containing cells.

Purpose-built for imaging assurance

Always in focus

To manage variation across multi-well plates, proprietary laser focusing ensures optimal focal position in each and every well.

Right up to the edge

Solid evidence comes from clear single cell images. Sophisticated methodologies to maintain image clarity right up to the edge.

Clarity in purpose

Designed specifically for the needs of assurance of clonality, Cell Metric has a highly tuned brightfield optical path that maximizes the clarity of single-cell imaging for assured cell line development.

Fluorescence imaging for rare event detection

As a tool for workflow verification, Cell Metric offers the option of rapid rare-event fluorescent imaging and reporting.

Automated confluence determination

For the effective tracking of daily outgrowth, Cell Metric offers automatic measurement and reporting of confluency.

Why Cell Metric is the choice for leading laboratories

Tried, tested, demonstrated IND success

Used globally in most of the world’s leading pharmaceutical and biotherapeutics companies, Cell Metric is the leading solution for providing regulatory information on clonality for Investigational New Drug (IND) submissions.

Solid image based evidence of assurance

Cell Metric captures a timeline of high quality whole well imaging as solid evidence of clonal origin.Unmatched high clarity imaging designed for single cell detection, even if the cell is at the wall edge.

Confident submissions with automated clonality report

Cell Metric wraps up the story including imaging, time stamps, annotation and comments as a solid record of evidence ready for confident IND submission.

Save time, resources and financial investment

Such is the confidence in data originating from the Cell Metric, workflows, such as those involving sub-cloning, mini-pools or repeated limited dilution rounds, can be significantly compressed, saving time, resources and financial investment.

Technical Specifications

Spec Description
Dimensions (D x W x H)Cell Metric
12.8 x 18.3 x 19 "
Net Weight Cell Metric
77.16 lbs
Operating Conditions Indoor use only
Temperature: 50° F to 104° F
Humidity: 20% to 80% non-condensing
Altitude: Up to 2000M
Mains Supply: +/- 10% rated voltage
Electrical Supply Power Supply Input Voltage: 100-240V AV 50-60Hz 3A Single Phase
Power Supply Output Voltage: 24V DC – 250W
Power Supply Input Connection: IEC Input
Automated Plate Loader Electrical Supply Power Supply Input Voltage: 100-240V AV 50-60Hz 3A Single Phase
Power Supply Output Voltage: 24V DC – 400W
Power Supply Input Connection: IEC Input Fuse T8AH

Associated Products

Accessories – Cell Metric CLD Cassettes

Cell Metric CLD 10 plate cassette holder is the perfect location to store cloning plates during the single cell growth phase. Cassettes are ideally designed to hold the plates in-situ for easy transport as well as keeping the plates at distance from each other to allow incubator conditions to easily circulate plates and get to the cell culture during the growth phase.

Next Generation Cell Culture Growth Supplements

In the search for high-value cells, growth conditions can be optimized to support early growth conditions. InstiGRO™ products are proprietary animal component-free cell culture supplements for CHO and HEK cells which confer major growth and survival advantages within cell line development. Designed to work with VIPS automation, Cell Metric imaging or manual cell practices, InstiGRO can transform workflows with greatly enhanced successful colonies per plate. ​

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Solentim MatriClone™

High Viability iPSC Single Cell Cloning and Outgrowth.

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Applications

Cell Metric is the Perfect Choice for
  • Cell line development for biologics
  • Gene therapy for viral vector production
  • Cell Therapy for use with human and induced pluripotent stem cells

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