While medical labs differ in size and specialties, all share the goal of improving health outcomes by delivering accurate and timely patient results. Maintaining strict security and regulatory compliance can get in the way of fast turnaround times. We can help.
Busy labs rely on Advanced Instruments osmometers for routine serum and urine osmolality testing.
At Advanced Instruments, we’re thinking ahead to your next challenge, working to optimize your processes and increase efficiency whether you focus on clinical chemistry, microbiology, or hematology.
Advanced Clinical Solutions set the standard, delivering dependable medical lab instruments, forward thinking educational resources, and responsive support services.
Applications
Medical lab instruments that deliver accuracy and efficiency
For laboratories seeking premium, reliable osmometers that meet their everyday needs for workflow efficiency, patient results security and integrity, connectivity, quality control, and compliance with CAP and CLIA guidelines , Advanced Instruments Osmometers are the right choice.
Keep your labs running smoothly and in compliance with osmometers that use the industry preferred freezing point depression method to provide accurate patient results.

Application Notes & Whitepapers:
- Scientific Literature Review: The Importance of Measuring Osmolality in Monitoring and Managing COVID-19 Patients
- The Value of Osmolality Testing, Dr. Neville R. Dossabhoy
- The Value of Osmolality Testing in Emergency Medicine, Dr. David Schindler
- The Value of Osmolality Testing in Nephrology, Dr. Namrata Sharma Goel
- Osmometry Revisited, A Practical Guide to Its Clinical Use, David H. Lobdell, M.D.
Streamline workflow, save money and improve the quality and consistency of your bacterial cultivation. Automatically and easily create exact, repeatable environments to keep clinical labs productive so patients can potentially get treated faster and spend less time in the hospital.
With the Anoxomat anaerobic jar system by Advanced Instruments, you’ll get the flexibility to simultaneously maintain multiple types of anaerobic, micro-aerophilic, and capnophilic environments on your benchtop for fast and reliable bacterial growth and larger colonies.
The Anoxomat system speeds sample processing with the ability to move plates into and out of the micro-environment within minutes instead of the hours it takes with full-sized vacuum systems and anaerobic chambers. Everyone in the lab can accomplish more with Anoxomat.

Scientific Resource
Related Articles
- Summanen P, McTeague M, Väisänen M, Strong C, Finegold S. Comparison of recovery of anaerobic bacteria using the Anoxomat, Anaerobic Chamber, and GasPak Jar systems. Anaerobe 1999; 5:5-9
- Shanin M, Jamal W, Veghese T, Rotimi V. Comparative evaluation of Anoxomat and conventional anaerobic GasPak jar systems for the isolation of anaerobic bacteria. Medical Principles and Practice 2003; 12: 81-86
- Barenfanger J. Outcomes of improved anaerobic techniques in clinical microbiology. Clinical Infectious Diseases 2002; 35 (Supplement 1): S78-83
- McIntosh J, Bullock W. A new apparatus for the isolation and cultivation of anaerobic micro-organisms. The Lancet 1916; 87:768-770
Busy labs often look to automation to ensure timely sample processing, but analyzing CSF samples – especially those at clinically relevant low cell counts – can be time-consuming and challenging. For labs that want to improve results consistency and turnaround time, there’s an Advanced Solution that meets this need with GloCyte.
Our CSF cell counter automates handling of all CSF samples, detecting down to 1 cell/µL and delivering total nucleated cell (TNC) and red blood cell (RBC) results in less than 5-minutes using only 30 µL per test, GloCyte gives labs a reliable and efficient method for automating analysis of all CSF specimens.

References
- Malenke, K. Cerebral Spinal Fluid Testing: Current methods for CSF analysis and new cell count technology. Advance for the Administrators of the Laboratory. December 2016. Vol. 25(12):p 16.
Bring accurate and reliable total and direct neonatal bilirubin testing to any facility with the BR2 Bilirubin Stat Analyzer and Bilirubin Test Kit. The compact, portable design easily fits into any facility, whether it is a dedicated medical lab or a pediatrician’s office, and the low 30 µL sample volume requirement facilitates analysis of samples from neonates.

The Osmo1 osmometer is a very simple to use osmometer. The instrument is reliable, robust, accurate and very fast at collecting data. Overall it is a high quality instrument, accurate results, easy to use.

Haileab Ghebrekidan, Macrogenics
Popular Educational Resources

The Value of Osmolality Testing in Clinical Chemistry
Osmolality is a fundamental measurement of the total solute concentration of body fluids. It is a valuable clinical diagnostic tool.

CSF Cell Counting - an evaluation of the GloCyte system
Laboratory staff face many decisions when they encounter a cerbrospinal fluid specimen. Learn more about how the GloCyte CSF Cell Counter system performs.

Scientific Resource
The Anoxomat III Anaerobic Jar System gives superior results compared to gaspak sachet generating methods.
Osmometers For Clinical
All models support:
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Workflow Features | ||||
Best for labs with daily sample processing needs of: | >10/day | >10/day | 1-10/day | |
Sample volume | 100 µL | 20 µL | 20 µL | |
Sample introduction | Automated liquid handling | Sample cup | One-step direct sampling | |
Operating range (mOsm/kg H2O) | 0 – 4,000 | 0 – 2,000 | 0 – 2,000 | |
Test time (seconds) | 180 | 90 | 90 | |
Compliance Support Features | ||||
Supports CAP & CLIA compliance | ![]() |
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Supports HIPAA compliance | ![]() |
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Instrument Features | ||||
Integrated barcode scanner | ![]() |
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On-board printer | ![]() |
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Multi-language touchscreen display | ![]() |
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Username & password compatibility | ![]() |
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Multi-sample capacity | ![]() |
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Automated cleaning between samples | ![]() |
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Automated sample pipetting | ![]() |
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Temperature control method | Dry cooling (No heat-transfer fluid) | Dry cooling (No heat-transfer fluid) | Dry cooling (No heat-transfer fluid) | |
Data Management Features | ||||
LIS Connectivity | ![]() |
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USB | ![]() |
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Part # | A2O | OsmoPRO | Osmo1 | |
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The most reliable osmometer we've ever used. We recently purchased another unit. Maintenance is easy, quick, saves time. Very economical, QC's are always good including the standard 290 (within range, every run).

Maria Baquiran, VAMC

Clinical Services
Get the best performance from your instrument from the people who designed and built it. We provide a range of services and service plans to meet the different needs of our customers. Our certified Field Service Engineers provide on-site professional support for the installation, training, validation, and maintenance of your osmometers, anaerobic jar systems, and neonatal bilirubin stat analyzers.
Calibrators & Controls
Protinol™ Protein-based Controls
Manufacturer-recommended QC helps labs stay within CAP & CLIA regulation guidelines.
Renol™ Urine Osmolality Controls
Manufacturer-recommended QC helps labs stay within CAP & CLIA regulation guidelines.
Clinitrol 290 Reference Solution
Use Clinitrol to verify system calibration and as a daily system check to strengthen your laboratory’s quality control program.
Anaerobic Jar Systems
Anoxomat® III Jar System
This anaerobic jar system easily creates custom anaerobic and microaerophilic environments in as little as 5 minutes, achieving effective and rapid bacterial recovery in less time. It allows clinical microbiology labs to realize cost savings, increased productivity and improved workflow.
Palladox™ Disposable Sachet
The new single use Palladox disposable sachet is designed specifically to work with the Anoxomat System. The easy-to-use, catalyst will simplify your anaerobic sample testing by minimizing catalyst handling time.
Ergonomic Jars for Anoxomat
Our light-weight, Ergonomic jars, provide flexibility and ease-of-use for lab techs, while maximizing incubator and laboratory space.
CSF Cell Counters
GloCyte
GloCyte is the automated cell counter that can handle all CSF specimens – even those with clinically relevant low cell counts that fall below the linearity of other automated analyzers.
GloCyte improves result consistency and turnaround time compared to the manual hemocytometer method.
Neonatal Bilirubin Testing
BR2 Bilirubin STAT-Analyzer
The Advanced® BR2 Bilirubin Stat-Analyzer™ system provides fast, accurate results for both total and direct bilirubin levels in neonates requiring only a 30µL serum or plasma sample. Ideally suited for pediatric physician offices, hospital stat labs, or pediatric research laboratories.