OsmoPRO® MAX Automated Osmometer

The highest level of osmolality testing automation.

The main advantage offered by the OsmoPRO MAX over our existing machines is the ability to load the samples and then walk away – currently our staff have to sit with the existing equipment until the test is completed. With workloads going up and pressures on staffing that feature is really valuable and was the biggest benefit for our laboratory.”

Debra Beesley / Lead Biomedical Scientist, Clinical Biochemistry, Royal Preston Hospital

Unsurpassed automation and ease of use

Clinical laboratories are under intense pressure to balance the high demand for testing with the need to quickly get accurate results to physicians. Offering unmatched automation, ease of use, and workflow flexibility, the OsmoPRO MAX Automated Osmometer is built for labs of all sizes. Features like automated pipetting, continuous loading of primary tubes, onboard video instructions, and integrated barcode scanners minimize errors and simplify the testing process. The instrument takes walk-away osmolality testing to a new level.

Highlighted features
  • Primary tube sampling
  • Intuitive navigation
  • Automatic barcode scanning
  • STAT testing
  • Automatic replicate testing
  • LIS connectivity

Take ease-of-use and efficiency to new levels

Suited for laboratories of all sizes, the OsmoPRO MAX revolutionizes osmolality testing with innovative flow-through technology that eliminates the need for consumables by pipetting samples directly from primary tubes, performing testing and cleaning within the device. Continuous loading and unloading removes the need to batch test. Experience unparalleled automation, workflow flexibility, and data management combined with the gold-standard freezing point depression method to measure osmolality. The OsmoPRO MAX frees your staff to focus on other priorities while delivering the accurate and timely results clinicians need.

Built for Labs of all sizes

Low-volume labs

Simple and intuitive operation eliminates manual processes, minimizes errors, and promotes accurate and timely results.

Moderate-volume labs

Effortlessly process any volume of tests and focus on other laboratory priorities with the built-in automation, flexibility, and ease-of-use of the OsmoPRO MAX.

High-volume labs

Automated, continuous testing and cleaning streamlines high throughput testing with minimal user intervention.

Product Features

  • Automatically pipettes a sample directly from the primary tube
  • Performs testing and cleaning within the device
  • Eliminates the need for consumables

  • Calibration needed as infrequently as once a year
  • Designed for 24/7 operation to maximize uptime

  • Liquid handling system automatically detects the level of the sample in the primary tube
  • Ready-to-use system fluid automates cleaning between samples for up to 500 tests

  • Turntable for continuous loading and unloading
  • Eliminates workflow interruptions and improves turnaround times

  • Color-coded touchscreen
  • Intuitive user interface
  • Multi-language capability
  • Onboard video instruction guides users through cleaning, maintenance, and calibration workflows

  • Automatic upload to the AdvancedQC™ Peer Group Program to compare results with peers and spot changes in instrument performance
  • Lock-out capability enables supervisors to require passing QC before sample testing

  • Walk-away testing of replicates from the same primary tube

  • Integrated barcode scanner automatically scans the turntable to determine number of samples and sample IDs

  • Easily export data to your laboratory information system, a USB, or an optional printer
  • Two-level user access with supervisor-defined permissions provides peace of mind
  • Sample IDs, password-protected user IDs, and lot recording enable traceability
Sample typeSerum, plasma, urine
Measurement PrincipleFreezing point depression
Minimum Required Sample Volume170 μL
Sample CapacityContinuous loading of up to 500 samples
Resolution1 mOsm/kg H2O
Range0 to 2000 mOsm/kg H2O
Accuracy2 Mean value ±2 mOsm/kg H2O from nominal value between 0 and 400 mOsm/kg H2O (1 SD)
Mean value ± 0.5% from nominal value between 400 and 1500 mOsm/kg H2O (1 SD)
Mean value ±0.75% from nominal value between 1500 to 2000 mOsm/kg H2O (1 SD)
Precision2 Standard deviation ≤2 mOsm/kg H2O between 0 and 400 mOsmo/kg H2O
Coefficient of variation ≤0.5% mOsm/kg H2O between 400 to 1500 mOsm/kg H2O
Coefficient of variation ≤0.75% mOsm/kg H2O between 1500 to 2000 mOsm/kg H2O
DisplayTouchscreen with onboard video instructions
Memory capacity1,000 results / 10,000 events
Temperature effects3Less than 1 mOsm/kg H2O per 5 °C (9 °F) ambient temperature change
Supported LanguagesChinese, Czech, Danish, Dutch, English, French, German, Italian, Japanese, Korean, Portuguese, Spanish, Swedish
CommunicationUSB 2.0 Type A ports (3)
USB 2.0 Type B port (1)
Ethernet 10/100
RJ45 connector port (1)
Printer (optional)
Storage temperature-40 °C to +45 °C (-40 °F to +113 °F)
Electrical voltage100 to 240 VAC (50/60 Hz)
Power consumption60 Watts
Dimensions (D x W x H)14.0” (36 cm) W x 16.5” (42 cm) D x 18” (46 cm) H
Net weight13.5 kg (30 lb)
Shipping weight20.9 kg (46 lb)
WarrantyOne-year limited warranty on workmanship and parts
  1. Subject to change
  2. Accuracy and precision (within run) specifications apply to Advanced Instruments standards and reference solutions. Performance at Reference Conditions: 20°C to 25°C (68°F to 77°F); minimum of 30% relative humidity
  3. Operating Conditions: Temperature 18°C to 35°C (64°F to 95°F); 5 to 80% relative humidity (non-condensing)

Osmometer Calibration Standards and Reference Solutions

3MA552OsmoPRO MAX Calibration Set
3MA002Osmolality Linearity Set, 100-2,000 mOsm 5x2x2 mL
3LA028Osmolality Linearity Set 100-2,000 mOsm 5x2x5 mL
3MA029Clinitrol™ 290 Reference Solution, 10×2 mL ampules

Osmometer Control Solutions

3MA028Protinol 3-Level Osmometer Control 3x3x3 mL
3LA085Renol 2-Level Osmometer Control 2x4x3 mL

Supplies & Accessories

MAX500OsmoPRO MAX Maintenance Kit
552923OsmoPRO MAX Small Volume Inserts, package of 100
552921OsmoPRO MAX Tubes, package of 250
Osmolality Linearity Set

0, 500, 900, 1500, 2000 mOsm/kg H2O 5x 2x 2 mL Ampules

View Product
Protinol™ Protein-Based Controls & Renol™ Urine Based Controls

Protinol 3-Level Osmometer Control 3x3x3 mL Renol 2-Level Osmometer Control 2x4x3 mL

Learn more
Osmometer Calibration Standards

Available from 0-4000 mOsm/kg H2O 10 x 2 mL Ampules

View Product

Clinical Services

Protect your investment with an Advanced Care service agreement from Advanced Instruments. Take the worry out of service costs and have total peace of mind knowing that your instrument is covered.

Learn more

For laboratories seeking premium, reliable osmometers that meet their everyday needs for workflow efficiency, patient results security and integrity, connectivity, quality control, and compliance with CAP and CLIA guidelines, Advanced Instruments Clinical Osmometers are the right choice.

Keep your labs running smoothly and in compliance with osmometers that use the industry preferred freezing point depression method to provide accurate patient results.

See all of our Clinical Osmometers
All models support compliance with accreditation bodies for hospitals and clinical labs
Workflow Optimizations
Integrated barcode scanner
Multi-language touchscreen display
Multi-sample capability
Automatic cleaning between samples
Automatic testing
STAT testing & load more capability
Continuous loading and unloading
Programmable replicate testing
Badge scanning capability
Automatic sample identification
Primary tube testing
Onboard video instructions
Quality Control Features
Out of specification QC alert capability
Real-time QC status indicator
Primary vial control testing*
Data Traceability, Security and Flexibility
Sample ID traceability
User traceability
Two-level, password protected user access
Onboard results & events storage
Ethernet for LIS connectivity
Multiple USB connections
Specimen type Serum, plasma, urine Serum, plasma, urine Serum, plasma, urine
Minimum sample volume 150 µL 20 µL 20 µL
Osmolality test method Freezing point depression Freezing point depression Freezing point depression
Size (w/d, cm) 36 x 42 25 x 38 36 x 38
Part # OsmoPRO MAX OsmoPRO Osmo1
*With AI-branded controls Learn More Request Pricing Learn More Request Pricing Learn More Request Pricing
Editorial Article: How automated osmometers optimize clinical lab workflows

Hear from experts on how active customer collaboration helps to develop a clinical instrument designed to enable efficient, accurate and timely results crucial to enhance patient care

Read on Select Science
Editorial Article: Walkaway Osmolality Testing from the Brand you Trust

Printed in the October 2023 issue of Pathology and Practice, learn about osmolality and using automation to enhance this powerful screening tool.

Download Article
Application Note

Osmolality: A Crucial Medical Tool for a Vast Range of Use Cases

Download Now
Application Note

Tackling Staff Shortages by Optimizing the Testing Workflow

Download Now
Application Note

Clinical Osmometers: Meeting the Increasing Need for Workflow Efficiency

Download Now
Virtual Clinical Osmometer Demo

Re-watch our live, virtual demonstration and learn how the latest innovations in osmometry for clinical laboratories can help improve your lab’s productivity for patient sample testing.

Watch Now
Knowledge Center

Importance of Measured Osmolality

Learn More

Want to see the OsmoPro Max
live in action?


Request pricing

For a quotation, to arrange a demonstration, or for more information please contact us by phone or complete the form.

Austria: +49 695 0606 800
Belgium: +31 6 899 25902
France: +33 456 681 861
Germany: +49 695 0606 800
The Netherlands: +31 6 899 25902
United Kingdom: +44 740 890 1366

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Austria: +49 695 0606 800
Belgium: +31 6 899 25902
France: +33 456 681 861
Germany: +49 695 0606 800
The Netherlands: +31 6 899 25902
United Kingdom: +44 740 890 1366

Request a Virtual Demo

For a quotation, to arrange a demonstration, or for more information please contact us by phone or complete the form.

Austria: +49 695 0606 800
Belgium: +31 6 899 25902
France: +33 456 681 861
Germany: +49 695 0606 800
The Netherlands: +31 6 899 25902
United Kingdom: +44 740 890 1366