Osmo1® Single-Sample Micro-Osmometer

The gold standard for osmolality testing.

Advanced Instruments Osmo 1 Single [sample osmometer] is an exceptional product. It is user friendly and easy to train new employees and students. The user guide is extremely detailed and thorough and easy to follow along. The instrument is reliable and using only faults due to human error. Great product!

Lacey Campbell / Springhill Medical Center

Your laboratory deserves best-in-class technology.

With the Osmo1 Single-Sample Micro-Osmometer, we’ve bundled together accurate and reliable osmolality measurement with ease-of-use for efficient patient sample analysis. With a 90-second test time and onboard QC charts the Osmo1 helps your laboratory stay productive. Best for labs that process 10 or fewer samples per day or prefer a direct-draw instrument.

Highlighted features
  • Gold-standard freezing point depression method technology
  • Low sample volume requirements
  • Supports CAP, CLIA, and HIPAA compliance

Ideal for small sample volumes

Osmo1 is ideally suited for clinical laboratories that prefer to directly draw and test small sample volumes. It offers ease of use and the security and efficiency of electronic data management along with the industry-preferred freezing point technology to deliver accurate and precise results.

Industry Applications

For Clinical Labs

Great for smaller clinical labs that test urine, plasma, serum and stool osmolality. The Osmo1 combines easy to use features and data management security options that help you stay in compliance.

Product Features

  • Simply aspirate sample and load

  • Color-coded menu-driven operating system
  • Multi-language capability

  • Only 20 µL of sample required
  • Ideal for sample limited applications

  • Drop-in paper design
  • Easy printing and archiving of test results.

  • Built-in proximity sensor
  • Traceable sample identification
  • Reduce transcription errors

  • Flexibility of a 2- or 3-point calibration
  • Satisfy CLIA calibration verification requirements
  • Factory-calibrated and ready-to-use

  • Calculates sample statistics instantly
  • Issue warnings when quality control is out of range
  • Allows tracking of quality control data over time with an exportable Levey-Jennings chart

  • Password protected user accounts
  • Link sample ID and user ID to test results for improved traceability
  • Stores last 1,000 test records and 10,000 events for audit control

  • Ethernet connectivity for LIS and data management systems
  • Multiple USB ports for easy exporting

  • Industry-preferred freezing point depression method

  • Purchase instruments with peace of mind
  • Knowledgeable, experienced, and responsive support team
Specimen type Serum, plasma, urine
Sample volume 20 ± 1μL
Test time 90 Seconds
Sample capacity single sample
Unit mOsm/kg H2O
Resolution 1 mOsm/kg H2O
Sample throughput can process 20 samples in less than 1 hour
Range 0 to 2000 mOsm/kg H2O
Accuracy2 0 to 400 mOsm/kg H2O: mean value ≤ 2 mOsm/kg H2O from nominal value(1 SD)
> 400 to < 1500 mOsm/kg H2O: ≤ 0.5% mOsm/kg H2O from normal value (1 SD)
> 1500 to 2000 mOsm/kg H2O ≤ 1% mOsm/kg H2O from normal value (1 SD)
Precision2 (within run) 0 to 400 mOsm/kg H2O: standard deviation ≤ 2 mOsm/kg H2O
> 400 to < 1500 mOsm/kg H2O: coefficient of variation ≤ 0.5% mOsm/kg H2O
> 1500 to < 2000 mOsm/kg H2O: coefficient of variation ≤ 1% mOsm/kg H2O
Temperature effects3 Less than mOsm/kg H2O per 5 °C (9 °F) ambient temperature change
Communication Onboard printer, USB 2.0 Type A port(2), USB 2.0 Type B Port(1), Ethernet 10/100, RJ45 Connector port(1)
Supported languages Simple Chinese, Czech, Danish, English, French, German, Greek, Italian, Japanese, Korean, Portuguese, Russian, Slovak, Spanish, Swedish, Turkish
Storage temperature -20 °C to +45 °C (-4 °F to +113 °F)
Electrical voltage 100 to 240 VAC (50/60 Hz)
Power consumption 60 Watts
Dimensions (D x W x H) 38 cm x 36 cm x 38 cm (15″ x 14″ x 15″)
Net weight 6.0 kg (13.3 lbs)
Shipping weight 11.4 kg (25 lbs)
Warranty One-year limited warranty on workmanship and all parts except glass, Plastic, and part warranted by their makers
  1. Subject to change
  2. Accuracy and precision (within run) specifications apply to Advanced Instruments standards
    and reference solutions. Performance at Reference Conditions: 20 °C to 25 °C (68 °F to 77 °F);
    40 to 60% relative humidity
  3. Operating Conditions: Temperature 18 °C to 35 °C (64 °F to 95 °F); 5 to 80% relative humidity
    (non-condensing)
  4. Dimensions when Micro-Sample Test Kit is on the instrument

Osmometer Calibration Standards and Reference Solutions

SKC-Osmo1Convenience Kit (Includes: 133800, 3MA005, 3MA029, 3MA085, 3MA200, 3LA028, FLA835, 3MA028, 3LA085)
3MA029Clinitrol™ 290 Reference Solution, 10×2 mL ampules
3MA00550 mOsm/kg H2O Calibration Standard, 10×2 mL ampules
3MA085850 mOsm/kg H2O Calibration Standard, 10×2 mL ampules
3MA2002000 mOsm/kg H2O Calibration Standard, 10×2 mL ampules
3LA028Osmolality Linearity Set 100-2,000 mOsm 5x2x5 mL

Osmometer Control Solutions

3MA028Protinol 3-Level Osmometer Control 3x3x3 mL
3LA085Renol 2-Level Osmometer Control 2x4x3 mL

Supplies

133800Micro-Sample Test Kit: 500 chamber cleaners, 500 sampler tips, 1 plunger wire (Replaces 3MA800 – Sample Tips and Chamber Cleaners, 500/box)
3M0828APlunger Wire, 1 per order (Replaces 3M0828- Plunger Wires, set of 2. Please note: A plunger wire is included in every 133800, TECH250, and XT100 Micro-Sample Test Kit box.)
3M0825Ease-Eject 20-Microliter Sampler
3M0827Sampler Calibration Key

Accessories

FLA835Thermal Printer Paper, 5 rolls
Osmometer Calibration Standards

Available from 0-4000 mOsm/kg H2O 10 x 2 mL Ampules

View Product
Osmolality Linearity Set

0, 500, 900, 1500, 2000 mOsm/kg H2O 5x 2x 2 mL Ampules

View Product
Protinol™ Protein-Based Controls & Renol™ Urine Based Controls

Protinol 3-Level Osmometer Control 3x3x3 mL Renol 2-Level Osmometer Control 2x4x3 mL

Learn more

Clinical Services

Protect your investment with an Advanced Care service agreement from Advanced Instruments. Take the worry out of service costs and have total peace of mind knowing that your instrument is covered.

Learn more

For laboratories seeking premium, reliable osmometers that meet their everyday needs for workflow efficiency, patient results security and integrity, connectivity, quality control, and compliance with CAP and CLIA guidelines, Advanced Instruments Clinical Osmometers are the right choice.

Keep your labs running smoothly and in compliance with osmometers that use the industry preferred freezing point depression method to provide accurate patient results.

See all of our Clinical Osmometers
All models support compliance with accreditation bodies for hospitals and clinical labs
New!
Workflow Optimizations
Integrated barcode scanner
Multi-language touchscreen display
Multi-sample capability
Automatic cleaning between samples
Automatic testing
STAT testing & load more capability
Continuous loading and unloading
Programmable replicate testing
Badge scanning capability
Automatic sample identification
Primary tube testing
Onboard video instructions
Quality Control Features
Out of specification QC alert capability
Real-time QC status indicator
Primary vial control testing*
Data Traceability, Security and Flexibility
Sample ID traceability
User traceability
Two-level, password protected user access
Onboard results & events storage
Ethernet for LIS connectivity
Multiple USB connections
Specimen type Serum, plasma, urine Serum, plasma, urine Serum, plasma, urine
Minimum sample volume 190 µL 20 µL 20 µL
Osmolality test method Freezing point depression Freezing point depression Freezing point depression
Size (w/d, cm) 36 x 42 25 x 38 36 x 38
Part # OsmoPRO MAX OsmoPRO Osmo1
*With AI-branded controls Learn More Request Pricing Learn More Request Pricing Learn More Request Pricing
Application Note

Osmolality: A Crucial Medical Tool for a Vast Range of Use Cases

Download Now
Application Note

The Value of Osmolality Testing

Download Now
Webinar

Serum Osmolality Disorders — Importance, Evaluation And Treatment

Watch Now
Webinar

AUDIO: A Conversation with the CAP on Osmometer Quality Control

Listen Now
Knowledge Center

Freezing Point Depression Theory

Learn More
Knowledge Center

Importance of Measured Osmolality

Learn More

Want to see the Osmo1 live in action?

BOOK A VIRTUAL DEMO

What our customers say

The [Osmo1] is a valuable tool within our facility. The set up was extremely easy. There are a lot of features for programming if you require passwords for individual users or if you just want any lab personnel to be able to run a sample. ... . Maintenance is easy to perform, it is not time consuming, or something you need to dig out the manual for complex instructions. The supply pack has a sensor in it so when consumables need to be replaced it will auto-update the supplies and alert when supplies are >50...

Judy McCormick

Meno Ya Win Hospital

The Osmo1 is a wonderful instrument. You can rely on the results. When testing in duplicate the results are always within 2 of the original results. The analyzer is simple to use and maintain. I have used an analyzer like this for 15+ years and have never had an instrument related failure. Advanced Instruments offers the supplies that a medical laboratory scientist needs to perform linearities, quality controls, and set standards for this analyzer. ...

Regenia Zeringue

Sky Lakes Medical Center

Advanced Instruments Osmo 1 Single [sample osmometer] is an exceptional product. It is user friendly and easy to train new employees and students. The user guide is extremely detailed and thorough and easy to follow along. The instrument is reliable and using only faults due to human error. Great product!

Lacey Campbell

Springhill Medical Center

We love our Osmo1 single [sample osmometer]. It's simple to calibrate, clean, and maintain. The precision and accuracy is much better [than] our previous Fiske 210 model and the Protinol and Renol controls are very stable.

Lacey Campbell

Springhill Medical Center

The Osmo1 osmometer is a very simple to use osmometer. The instrument is reliable, robust, accurate and very fast at collecting data. Our department have been using it for over a year and a half and I have never experienced any big issue with it. ... Overall, it is a high-quality instrument, accurate results, easy to use.

Haileab Ghebrekidan

Macrogenics

The Osmo1 follows in the footsteps of its predecessors like the 3250. The introduction of barcode scanning and touch screen has provided better functionality and connectivity. The device has rock solid performance and uses the same supplies as the 3250. Advanced Instruments is definitely the market leader when it comes to osmolality measurement with accurate results for patient clinical use in a 24/7 environment.

Ken Onuska

Halton Healthcare

I am the technical specialist for the area. The ease of use and small sample volume needed are what has impressed me the most [about the Osmo1]. Also, the programming ability. The team we deal with here in the Halifax area are exceptional and are always here to help in any way necessary. The instruments allow us to produce not only a quality result, but we do it the most efficient way possible.

Erica Mayo

NSHA

Great customer service, the FSE was knowledgeable and personable. The analyzer, which was an updated version of our previous osmometer, provides ease of use, updated technology, and produces accurate and reproducible results. The Osmo1 single sample micro osmometer makes maintaining regulatory compliance simple.

James DeGori

HNL Lab Medicine

The Osmo1 was very easy to set up. Instructions were easy to follow. I like that the printer is incorporated into the analyzer and that the consumable boxes have sensors that count down the number of tips left. Very easy for staff to use.

Karen Thompson

SSM Health DePaul Hospital - St.Louis

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Austria: +49 695 0606 800
Belgium: +31 6 899 25902
France: +33 456 681 861
Germany: +49 695 0606 800
The Netherlands: +31 6 899 25902
United Kingdom: +44 740 890 1366

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For a quotation, to arrange a demonstration, or for more information please contact us by phone or complete the form.

Austria: +49 695 0606 800
Belgium: +31 6 899 25902
France: +33 456 681 861
Germany: +49 695 0606 800
The Netherlands: +31 6 899 25902
United Kingdom: +44 740 890 1366

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