Solentim Cell Metric® X Clonal Imager

Reduce time and effort with artificial intelligence driven by automated evidence of clonality

Cell Metric had the best whole-well imaging capabilities and clonality reports and, when we demoed the instrument, we were convinced by the robustness of the system and very high image quality.

Tom Kelly / Janssen

For unrivaled clonality assurance with high-contrast imaging, make the trusted standard your standard.

Cell Metric X delivers high-quality whole-well imaging, setting a new bar for faster clonality verification to accelerate your path to IND submission-with zero compromise in quality. With the power of artificial intelligence-based Automated Evidence of Clonality, CHO, HEK, and iPSC cells are identified automatically on day 0 without user bias. Know on day 0 that your experiment was a success. Get unrivaled clonality assurance in a fraction of the time and effort—with Cell Metric X.

Highlighted features
  • Automated Evidence of Clonality
  • STUDIUS™ integration
  • Walk-away automation
  • High throughput 10-position plate stacker
  • Automated system setup for ease-of-use and reduced learning curve

Cell Metric X Clone Imager with Automated Assurance

Cell Metric X utilizes automated evidence of clonality that saves the user time by pre-identifying cell locations. New high precision confluence scanning option saves time by showing optimal timepoint for cell expansion. High quality imaging and highly tuned brightfield optical path enable fast and confident identification of cells.

Highlighted Features

Clonal Assurance on Day 0

Cell Metric set the standard for high-contrast imaging. Cell Metric X raises the bar, delivering faster, easier clonality verification on day 0 to accelerate your path to IND submission—with zero compromise in quality.

Simplify Clonal Assurance with Artificial Intelligence

Identify single-cell clones on day 0 with artificial intelligence-based Automated Evidence of Clonality (AEC) and move from testing to IND submission weeks faster.

Streamline Your Process

Cell Metric X portfolio includes a 10-position plate stacker, and compatibility with third party robotics. Integration with the STUDIUS™ data management platform and the entire Solentim Ecosystem streamlines decision making and automates clonality reports.

Product Features

  • STUDIUS™ data management platform
  • Report compiles images, time stamps, annotations and comments as a solid record of evidence
  • Confident IND submission

  • Data from VIPS® PRO, ICON™, and Cell Metric X
  • Full visibility into the CLD workflow from seeding through to final selection

  • Used by leading pharmaceutical and biopharmaceutical companies and CDMOs worldwide
  • Leading solution for compiling evidence of clonality for Investigational New Drug (IND) submissions

  • High-contrast, high-resolution imaging
  • Right-up-to-the-edge imaging for optimal single-cell detection
  • Allow for fast & confident identification of cells

  • AI-driven algorithm for extremely precise confluence readout
  • Assess clonal outgrowth of various cell morphologies including iPSCs and MSCs
  • Easy clone selection based on clonality and growth rates.
Spec Description
Dimensions (D x W x H)12.8" x 18.3" x 19" (32.5 cm x 46.5 cm x 48.2 cm)
Net Weight 77.16 lbs (35 kg)
Operating Conditions Indoor use only
Temperature: 50° F to 104° F (10-40° C)
Humidity: 20% to 80% non-condensing
Altitude: Up to 2000M
Mains Supply: +/- 10% rated voltage
Electrical Supply Power Supply Input Voltage: 100-240V AV 50-60Hz 3A Single Phase
Power Supply Output Voltage: 24V DC – 250W
Power Supply Input Connection: IEC Input
Automated Plate Loader Electrical Supply Power Supply Input Voltage: 100-240V AV 50-60Hz 3A Single Phase
Power Supply Output Voltage: 24V DC – 400W
Power Supply Input Connection: IEC Input Fuse T8AH

STUDIUS™

The smartest decision-making platform in cell line development. STUDIUS provides a more consistent cell line development workflow for scientists creating biotherapeutic Master Cell Banks, enabling faster and more confident decision making.

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Next Generation Cell Culture Growth Supplements for CHO & HEK

In the search for high-value cells, growth conditions can be optimized to support early growth conditions. InstiGRO™ products are proprietary animal component-free cell culture supplements for CHO and HEK cells which confer major growth and survival advantages within cell line development. Designed to work with VIPS automation, Cell Metric imaging or manual cell practices, InstiGRO can transform workflows with greatly enhanced successful colonies per plate.

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Solentim iPSC Matrices

MatriClone and Clinical Manufacturing Grade Laminin are matrices designed to support iPSC growth in single seeding workflows while maintaining pluripotency. These matrices are optimized for ‘in-solution’ seeding and optically suited for automated imaging.

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Solentim Cell Metric® X Clonal Imager is the perfect solution for:

  • Biologics development and production
  • Cell and gene therapy and viral vector production
  • Induced pluripotent stem cell (iPSC) production
Solentim VIPS® PRO
High efficiency, single cell seeding and imaging platform

High efficiency, single cell seeding with image-based proof of clonality for GMP-compatible workflows

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Solentim ICON™
Clone & Protein Biologic Analyzer

Analyze VCD, titer and productivity for selection of the highest value clones.

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STUDIUS™
Data management software platform

Data management for the highest level of consistency across the CLD workflow

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Services

Protect your investment with an Advanced Care service agreement from Advanced Instruments. Take the worry out of service costs and have total peace of mind knowing that your instrument is covered.

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Application Note

Automated Evidence Of Clonality

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Case Study

Doubling The Speed Of Cell Line Development In A Large Pharmaceutical Company

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Scientific Poster

Proof that can travel – Documented clonality report for regulatory submission

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Case Study

FACS bulk enrichment in combination with the VIPS and Cell Metric delivered significant savings for a CDMO

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Webinar

Using Artificial Intelligence (AI) to Identify Clonally Derived Cell Lines. See the Future Today

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Knowledge Center

Assurance of Clonality

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Want to see what the Cell Metric® X can do for your workflow?

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What our customers say

Before this instrument, all our clonal analysis was done manually. We used to spend hours on the microscope looking for wells containing colonies possibly derived from single cells. Now, everything is automated, we since we can track the cell growth over time, we can be absolutely sure that a particular clones is derived from a single cell.

Rodrigo Santos

Horizon Discovery

Very easy to use and produces good quality cell images, which are essential when monitoring outgrowth after limiting dilutions. The 10 plate cassette with automatic loading is very helpful for high throughput experiments, and the versatility of plate type makes the cell metric even more useful.

Ngarangi Mason

Horizon Discovery

The Cell Metric was designed with the end user in mind. Setup and use are easy and the ability to generate a clonality report at the end of a project is fantastic. I would highly recommend taking a very close look at the Cell Metric before adding any imaging system to a CLD workflow.

Ray Davis

RuffLife Consulting

The Solentim Cell metric has become a crucial instrument in our cell line development process. The instrument has allowed us to create reliable and consistent data which in turn results in us being able to track our cell lines and compare them to each other with ease. Images produced by this instrument are always of high quality, and it is easy to train new member of the team on this platform as the system is very user-friendly! ...The instrument is certainly worth the money we paid as it has allowed us to determine monoclonality and track colony growth ...

Emily Agro

Ultragenyx Pharmaceuticals

Cell Metric had the best whole-well imaging capabilities and clonality reports and, when we demoed the instrument, we were convinced by the robustness of the system and very high image quality.

Tom Kelly

Janssen

The Solentim ecosystem, [VIPS , Cell Metric, ICON], allowed Wheeler to rapidly develop and launch a standardized cell line development service that is integrated with a scalable drug substance process.

Mike Brem

Wheeler Bio

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Austria: +49 695 0606 800
Belgium: +31 6 899 25902
France: +33 456 681 861
Germany: +49 695 0606 800
The Netherlands: +31 6 899 25902
United Kingdom: +44 740 890 1366

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For a quotation, to arrange a demonstration, or for more information please contact us by phone or complete the form.

Austria: +49 695 0606 800
Belgium: +31 6 899 25902
France: +33 456 681 861
Germany: +49 695 0606 800
The Netherlands: +31 6 899 25902
United Kingdom: +44 740 890 1366

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