Advanced Instruments at BioProcessing International | Advanced instruments

Advanced Instruments at BioProcessing International

Be the first to hear about our NEW VIPS PRO for single cell seeding!

We invite you to join us at BioProcessing International Conference in Boston for our scientific presentation and to see the unveiling in-person at booth #618!

Proof or Probability?

Latest Technology for Assurance of Clonality in Cell Therapy Manufacturing

Thursday, September 29 | 11:15 AM | Room 209

Marta Rucka
Global Product Leader
Advanced Instruments


Cell and gene therapy (CGT) is one of the most promising and fastest growing sectors in biopharmaceutical industry. This is matched by increasing demand for novel technologies designed to improve workflow efficiency, while ensuring confidence in data. One of the requirements in the CGT manufacturing is ability to demonstrate product safety and consistency. The regulatory agencies expect that each therapeutic cell line is clonally derived, thus originates from a single progenitor cell. Traditionally, this was achieved by subcloning using limiting dilution (LD) method. However, due to the time and labor required combined with the low seeding efficiency and no evidence of clonality, many scientists are moving away from LD. Many alternative technologies utilise seeding and imaging of a single cell prior to dispensing. However, this approach often does not provide evidence of clonality, but only probability.

In this talk we will discuss how the latest developments from Advanced Instruments which provide solutions for single cell cloning, advanced cell detection, high-quality imaging, and data analysis. Our unique approach offers confidence in data and assurance of clonality as perfect solution for CGT in both process development and GMP-settings.

Advanced Instruments Introduces Solentim VIPS™ PRO, A High Efficiency Single Cell Seeder to Optimize Cell Line Development Workflows

VIPS PRO delivers powerful and efficient seeding technology and definitive proof of monoclonality for workflow productivity and confidence.

VIPS PRO revolutionizes cell line development (CLD) workflows by combining powerful seeding technology with two-step, image-based proof of monoclonality and proprietary Artificial Intelligence-driven cell recognition for increased productivity and confidence.

Come visit us at Booth #618!

Not at BPI? Contact us to learn how VIPS PRO could revolutionize your workflow