MVS QualAssure® Solutions

Liquid Class Optimization for Decreased Variability

MVS QualAssure solutions mimic some of the most common reagents used with liquid handlers, so that you can optimize the performance of your assay, and tailor your liquid handler settings to your specific liquid class, tips and plates. By making the necessary adjustments to your liquid handler, you can ensure accurate and precise liquid handling and minimize the variability of your results.

How It Works:  MVS QualAssure solutions contain two dyes: red and blue. Each solution covers a designated target volume range. As the volume-of-interest decreases, the appropriate QualAssure contains an increased concentration of red dye, thereby maintaining constant signal strength to the plate reader detector. The blue dye is used as an internal standard to measure the solution depth in every well. MVS QualAssure are solutions prepared by Artel and conform to rigorous performance specifications.

Metrological Traceability

Metrological traceability is maintained to the international system of units (SI). Photometric standards are calibrated at the National Physical Laboratory of the United Kingdom. Qualification of reference spectrophotometers meets applicable standards such as the United States Pharmacopeia (USP), ISO, CLSI, and ASTM International.

Solution Manufacturing

• Solutions are manufactured in a HEPA filtered clean room.
• Precise chemical formulations are made according to gravimetric and volumetric standard operating procedures by qualified chemists.
• Solutions are manufactured, preserved and sub-micron filtered to ensure stability and performance.
• Release testing is done in Artel’s accredited ISO 17025 laboratory.

Quality Testing

• Calibration of all solutions is performed with very precise methods.
  • ±0.0004 AU for 730 nm measurements
  • Accuracy measured with uncertainty as low as 0.033%
• The Artel laboratory maintains an ISO 17025 scope of accreditation for calibration methods used to test all manufactured solutions.
• All laboratory chemists go through a rigorous training and qualification plan prior to performing methods.
• Proficiency testing via inter-laboratory and intra-laboratory comparison monitors the competence of all laboratory chemists.
• The laboratory environment meets the requirements of ISO 8655 and NIST SOP 14.
• The laboratory maintains a registered quality management system according to ISO 9001 which ensures document control, record control, risk/opportunity, improvement, corrective action, internal audits and management review.

Filling & Labeling