Artel MVS® Multichannel Verification System

Simple volume verification with results in less than 10 minutes

The Artel MVS has been a huge help for our lab in validating volumes on new automated liquid handlers. Always gives consistent results, easy to use, software is extremely straightforward, and any time we have an issue, it's super easy to get help from the Artel team. Thank you!

Leah Chong / Invitae

Simple volume verification with results in less than 10 minutes

Compatible with virtually all automated liquid handling systems and multichannel handheld pipettes, the Artel MVS sits on a mobile workstation for portable rapid calibration, verifications and optimization of dispensed volumes with high precision and accuracy. Understand and manage the performance of your automated liquid handlers, multichannel pipettes, labware, operators, and more.

Highlighted features
  • Wide Volume Measurement
  • Eliminates Need for Rigorous Environmental Conditions
  • Simplified Verification and Calibration
  • Results Traceable to SI

Ensure the performance of your multichannel liquid handling devices

The MVS’s unique, dual-dye photometric measurements are robust against environmental influences and traceable to SI units to enable comparison across operators, protocols, equipment, and locations. Using the Calibrator Plate, Verification Plates, and an Artel-certified Plate Reader, the MVS ensures a continuous chain of traceability to national and international standards.

Compliance Suite offers essential features for facilities that comply with Title 21 CFR Part 11

The MVS conforms to the Dual-Dye Ratiometric Photometric Method described in ISO 23783-2:2022, and the Ratiometric Photometric Method described in ISO/IWA 15:2015 for automated liquid handling systems. It can be used to fulfill test and calibration requirements of handheld multichannel pipettes according to ISO 8655-7:2022. The MVS can be used to fulfill test and calibration requirements of handheld or automated liquid handling systems according to CLSI QMS23:2019, ISO 17025:2017, cGMP, and cGLP. ArtelWare Software can be used in laboratories compliant to 21 CFR Part 11.

Optional Compliance Suite addon features:

  • unique user account credentials ensure all actions are tracked with a full audit trail
  • user groups with specific privileges can be established
  • new plans and plan updates require approval and are given specific version numbers
  • laboratory managers can set an electronic signature requirement at any step (for full compliance with the lab’s own quality system)
  • each auditable action requires audit comments when complete, and audit data is saved in secure SQL databases which may be placed on a mapped server to ensure regular back-ups

Dispense solutions

Dispense the Artel QualAssure® solution and Diluent into a Verification Plate & mix. No need to prepare in-house dyes or generate standard curves.

Read the plate

The MVS measures absorbance values and generates precise volume measurements independently in each well of the Verification Plate. No weighing is involved and environmental controls are not required.

Verify and record performance

The software automatically calculates accuracy and precision for individual volume values, for each tip or channel and provides summary statistics by well, row, and column. Results are stored in ArtelWare, and reports are ready to print or export.

FAQs

The MVS conforms to the Dual-Dye Ratiometric Photometric Method according to ISO 23783-2:2022, and the Ratiometric Photometric Method described in ISO/IWA 15:2015 for automated liquid handling systems. It can be used to fulfill test and calibration requirements of handheld multi-channel pipettes according to ISO 8655-7:2022. The MVS can be used to fulfill test and calibration requirements of handheld or automated liquid handling systems according to CLSI QMS23:2019ISO 17025cGMP, and cGLP. ArtelWare Software can be used in laboratories compliant to 21 CFR Part 11.

Artel has evolved our brand to better align with our values and the customers we serve, and to symbolize where we are today. But the Artel mission has remained the same – to help labs achieve their goals for quality, productivity, and compliance. One of the changes made during the transition was consolidating the array of verification solutions under the new QualAssure label. The QualAssure name describes the assurance of accurate, precise, and reproducible data that customers have come to expect from using Artel technology, products and services. The products themselves are the same proven formulations and volumes as users have come to depend on and customers do not need to change their ordering processes.

The MVS Multichannel Verification System is the first commercially-available volume verification system. It includes equipment, software, QualAssure solutions and characterized microtiter plates to allow operators to quickly and easily verify the liquid delivery performance for automated liquid handlers and multichannel pipettes within minutes. The MVS also allows for multichannel pipette operators to be assessed for pipetting competency and then trained accordingly. The system is suitable for liquid volume measurements from 0.01 µL to 350 µL and dilution measurements up to 1:2048 of the starting material. The MVS is positioned on a mobile workstation to allow for portable, convenient volume verification of pipettors in multiple locations.

MVS employs a dual-dye, dual-wavelength, ratiometric absorbance-based measurement method for calculating the volume of sample dispensed into a well of a microtiter plate. The results of the verification tests are traceable to national and international standards. Specially formulated QualAssure solutions containing dyes of known concentration are dispensed into dimensionally-characterized microtiter plate wells. The plate is mixed on a microtiter plate shaker to ensure homogeneity of samples. Absorbance readings are taken in the plate reader at 520 nm and 730 nm. The ArtelWare software creates a summary report containing the calculated dispensed volume for each dispensing tip. Accuracy and precision of the dispensed volumes are measured against user-defined tolerance limits and failing values are flagged in the report. Summary statistics by well, by row, and by column are also contained in the summary report in a secured database.

Artel has designed the MVS to be universally applicable to virtually any liquid handler. These devices must be capable of dispensing into a standard 96- or 384- well microtiter plate.

The MVS is sold as a complete system. The system components include a customized Plate Reader, a unique Calibrator Plate, a microtiter Plate Shaker, a bar code reader, a portable computer with ArtelWare software and a mobile workstation. On-site system installation and validation are also included with an MVS purchase. 

No, we do not support the use of other plate readers at this time.

The MVS includes a mobile workstation for convenient verification of equipment in multiple locations throughout a laboratory or facility.

Yes, the MVS is a convenient way to verify the accuracy and precision performance of each independent channel at the same time.

The MVS allows for analysis of accuracy and precision for each independent dispensing channel simultaneously, which saves labor and liquid handler down-time. It is relatively immune to environmental conditions and provides measurements traceable to national and international standards. The MVS QualAssure solutions are manufactured by Artel to tight tolerances using ISO-acknowledged methods. There is no need to generate standard curves. MVS provides standardized results making it possible to compare instrument performance between makes and models of liquid handlers as well as between locations, i.e., 2 µL dispensed by liquid handler X on Tuesday in Boston can be directly compared to 2 µL dispensed by liquid handler Y on Friday in San Diego. Please refer to the MVS White Paper for more information.

The MVS does not require FDA approval because it is not directly associated with human samples or specimens. The MVS results are traceable to national and international standards.

The only regular maintenance required is the recertification of the MVS Calibrator Plate, which has a shelf-life of 1-year. At the one year mark, the Calibrator Plate must be shipped back to Artel for the recertification process. Aside from Calibrator Plate recertification, the only other routine maintenance required is the occasional replacement of the lamp in the Artel Plate Reader (dependent on plate reader used), which can be easily completed by the user.

System Performance with 96 well MVS Verification Plate

Time Requirements< 5 Minutes
Tip Configurations1, 2, 4, 6, 8, 12, and 96
Traceable Volume Range0.1000 - 350.0μL
Operating Volume Range0.0001 - 350 μL
Operating Temperature15 - 30° C
Traceability to national & international standardsYes

System Performance with 384 well MVS Verification Plate

Time Requirements< 10 Minutes
Tip Configurations1, 8, 12, 16, 24, 96,
and 384
Traceable Volume Range0.0100 - 55.00μL
Operating Volume Range0.0001 - 55.00μL
Operating Temperature15 - 30° C
Traceability to national & international standardsYes

MVS Computer (recommended minimum requirements)

Processorx64 Processor: 2.4 GHz
(recommended 4 or more cores)
Memory4 GB (recommended min. 16GB)
I/O Ports3 USB Connectors
NetworkGigabit Ethernet or 802.11n wifi
Storage40 GB of hard drive space
Supported Operating SystemsWindows® 10 or Windows® 11
SQL Server2019, 2017, 2016, and 2014
in Express, Standard
and Enterprise Editions

ARTEL 800TSNB PLATE READER

Dimensions (DxWxH)41.9 x 38.1 x 17.8 cm
Weight9.97 kg
DisplayTouch screen
Light sourceTungsten gas filled bulb
Wavelength selectionMetal oxide interference filters
Center wavelengths:
520.2 nm (bandwidth at half-max = 6.2 nm)
730.5 nm (bandwidth at half-max = 10 nm)
Additional filters405 nm, 450 nm, 490 nm
COM PortUSB
Power requirementsVoltage: 90 – 260 VAC
Frequency: 50 – 60 Hz
Current: 2 A maximum

MVS TITER PLATE SHAKER

Dimensions (DxWxH)142 x 99 x 48.2 mm
Amplitude2.0 mm orbital
Shaking speed range200 to 3000 rpm
Power requirementsExternal power supply
100-240 V AC
50-60 Hz

MVS CALIBRATOR PLATE

Storage Temperature15 - 25 °C in protective case
out of direct light
Operation Temperature15 - 30 °C
Recalibration12 month factory
recalibration required
Shelf life1 year

MVS BAR CODE READER

Dimensions (LxWxH)104 x 71 x 160 mm
Weight147 g
MVS QualAssure® Solutions

Optimize your automated liquid handlers with the ideal liquid for your application.

Learn more
ArtelWare™ Software

Ensure your liquid handlers and pipettes are performing properly with full suite of management tools.

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Liquid Handling Service

Bring a liquid handling expert into your lab to help with your automated liquid handling workflow.

Learn more

Consumables

MVS-201Baseline Solution
MVS-202Diluent Solution
MVS-203Aqueous QualAssure A
MVS-204Aqueous QualAssure B
MVS-205Aqueous QualAssure C
MVS-206Aqueous QualAssure D
MVS-207Aqueous QualAssure E
MVS-210Stock Solution 1
MVS-212Stock Solution 2
MVS-214Aqueous QualAssure HV
MVS-216DMSO QualAssure E
MVS-217DMSO QualAssure C
MVS-218DMSO QualAssure D
MVS-219PCRMix QualAssure C
MVS-220PCRMix QualAssure B

Accessories

MVS-150MVS Instrument Carrying Case - Case with wheels for MVS
MVS-23096-well Verification Plates
MVS-231Verification Plate Covers
MVS-245384-well Verification Plates

The Artel MVS® Multichannel Verification System is the perfect system for:

  • Optimizing liquid classes
  • Facilitating of scale-up and method transfer
  • Developing, troubleshooting, and validating assays, methods, and SOPs
  • Ensuring reproducibility of assay results
  • Site acceptance testing and establishing baseline performance of new equipment
  • Verifying performance before and after maintenance
  • Assessing performance of other essential liquid handling equipment such as plate shakers, plate washers, and bulk dispensers
Cell and Gene Therapies

The research and development phase of cell and gene therapies is critical. Laboratories must ensure the efficacy, potency, and safety of new treatments. Whether you are working with scarce patient-derived samples or dealing with low yields on your viral capsid harvest, you need your assays to work. Under-dispensing can cause assay failure while over dispensing can drive up cost by being unnecessarily wasteful.

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Commercial Diagnostics

The constant emergence of new diseases pushes the expansion for new lab tests and increases test volumes. This brings increasing pressure for faster detection, notably in the field of infectious diseases and cancer. Automation becomes a necessity to improve productivity and ensure consistency, thereby decreasing turnaround time and replacing manual error-prone tasks.

Learn More
Process Development

Shortening time to market is not only critical to meet demand, but it is also essential to stay ahead of competitors. Automating and taking control of your assay workflows can make your process more efficient by breaking down the assay workflow into modules that are individually optimized – therefore improving end-to-end assay performance.

Learn More
MVS Specifications

Learn system performance specifications with 96 and 384 well MVS verification plates. Includes computer requirements and software specifications.

Download Specifications
Case Study

SEKISUI XenoTech Ensures Quality And Productivity With The MVS

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White Paper

Process Optimization For Assays: A Framework For Controlling Variability And Optimizing Assay Performance

Download Now
Webinar

New And Revised ISO Standards

Watch Now
Knowledge Center

Precise liquid volume measurement with ratiometric photometry technology.

Learn More
Case Study

Beckman Coulter improved customer satisfaction, expanded OQ sign-ups with an MVS

Download Case Study

Ready to transform your automated liquid handling process?

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What our customers say

The MVS has been a great asset to my team's measurement capabilities for the past 10 years. We just recently purchased the newest version of the MVS. We had a lengthy delay in our PO process and Nate the Artel Account manager has been very understanding and has helped us the entire way. The system makes accuracy and precision testing for liquid dispensing very efficient. When we need additional supplies or support questions the Artel staff has always been top tier. We plan to try the new Artelware software and move away from the older Data manger software.

Dan Baumgartner

Metrologist, Bayer

The Artel MVS simplifies fluid verification of all automated liquid handlers and multichannel pipettes. The system is fast, calculates all plate and well statistics (Relative Inaccuracy, Coefficient of Variation, Standard Deviation and Mean) and it is simple to set up and use. For all of its capabilities and low-cost point...the MVS is one of the best value purchases I have ever made for my lab.

Mark Orlowski

Pfizer

The Artel MVS makes it so easy to do a monthly verification that the 96 channel CORE head on my Hamilton Vantage is dispensing the correct volumes. Doing the confirmation gravimetrically would be so time consuming, but using the Artel dyes and the MVS makes it something one person can do in a single morning. The software is easy to use, and the instrument has not had any maintenance issues.

Katherine Schneider

Pfizer

The Artel MVS has been a huge help for our lab in validating volumes on new automated liquid handlers. Always gives consistent results, easy to use, software is extremely straightforward, and any time we have an issue, it's super easy to get help from the Artel team. Thank you!

Leah Chong

Invitae

The MVS system is extremely useful for periodic performance QC testing of high-throughput liquid handlers, high-throughput liquid handler calibration, and various liquid handler/single channel pipette tip type/lot QC. The MVS system requires minimal maintenance and MVS manager software is intuitive to use and flexible to set up various plate layouts to meet user’s need. The customer service is very responsive and helpful. They provide a notification for calibrator plate re-certification annually ...

Hyun-Wu Lee

Canada's Michael Smith Genome Sciences Centre

The [Artel MVS] product is accurate and reliable. With the addition of the pre-owned models of MVS readers, it also becomes affordable. The expansion of the dye solutions to include MasterMix and Serum along with their original aqueous offering makes Artel a definitive liquid class setup solution. The FSE performing setup and the account manager were on-time, responsive, and supportive during install and (most importantly) afterwards.

Kevin Kim

Avellino Labs

The Artel application scientist is easy to work with, knowledgeable about interpreting test data and giving advice, and flexible to help onsite if needed. I would recommend the Artel MVS because it saves time and material cost. Most important is having a standard method to calibrate different pipettes and optimize liquid class on automated liquid handlers while managing the sources of variability systematically.

Michelle Mak

10x Genomics

The MVS [has] made verifications so much more efficient. It also enabled us to detect an issue with one of our instrument onboard pipetting devices. The customer service is great and using this system makes accreditation assessments much easier!

Beth Johnson

KY Division of Lab Services, DPH

The [Artel MVS] is easy to use, gives accurate and reliable results. It's a great way to quickly determine the functioning of the automation systems that we install and maintain.

Thobias Haakman

Beckman Coulter

The MVS system is fairly intuitive to use. Not only can we use this for our internal automated liquid handler volume verification, tip test and calibration work, we have been using the system to offer external volume verification service to our collaborators. The system is very durable without significant issues and easy to maintain. MVS reagent orders are always processed and delivered in a timely manner. Our regional specialist periodically checks in to ask if the system is working as expected.

Hyun-Wu Lee

Canada's Michael Smith Genome Sciences Centre

Once we brought [the Artel MVS] into the lab, we realized we could push to small volumes. We typically work beyond the liquid handler’s specifications, and we can do this because we have Artel to verify their performance.

Robert Grbac

SEKISUI XenoTech

We were doing liquid class development and realized that we couldn’t get anything <10 uL to pass. With the MVS, I was able to optimize our liquid classes in just 6 tests! We took it from a 16% inaccuracy down to 1.6% at 10 uL. Piece of cake when you’ve got something like the MVS in your corner.

Douglas Brown

CRL Clinical Reference Laboratory

The Artel MVS System has greatly improved our laboratory quality processes, not only streamlining instrument qualifications but accelerating verification and validations.

Chris Trefill

SummerBio

We rely on the MVS for verifications and liquid class development and optimization…

Thai Truong

Janssen R&D

The [Artel MVS] simplified and streamlined our QC process…

Natalie Grow

Bristol-Meyers Squibb

The MVS system has been vital to our lab operations.

Hyun-Wu Lee

Canada's Michael Smith Genome Sciences Centre

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Belgium: +31 6 899 25902
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United Kingdom: +44 740 890 1366

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