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Assessing Dry Eye Disease
with osmolality measurement


The Advanced® Tear Osmometer is the first
automated tear quality assessment instrument to reach the commercial marketplace. This freezing point osmometer measures tear film osmolality, which is recognized in the Dry Eye Workshop (DEWS) committee’s definition of dry eye disease.


    Key points

  • Reliable measurement
  • 500nL sample size
  • Consistent
    performance
  • Class I exempt

Research, industry, and clinical applications

The Tear Osmometer (and included computer) is a tool that assists clinicians in classifying, monitoring, and diagnosing patients with keratoconjunctivitis sicca (KCS) or dry eye disease. The instrument can also be used to screen for dry eye prior to LASIK or other types of refractive surgery.

Reliable measurement

Unlike other methods for determining the concentration of solutes dissolved in solution, such as vapor pressure or conductivity, the freezing point method determines the concentration of a solution by accounting for all components that affect osmolality.

The Advanced Tear Osmometer, showing osmometer, computer, and mouse
AI Part Number: 3100
Picture of Tear Osmometer with laptop display
Datasheet
Advanced Tear Osmometer datasheet

Scientific Posters
Evaluation of a new tear osmometer instrument for repeatability and and accuracy

Correspondence of tear film osmolality and dry eye symptoms...

The performance of a novel nanolitre osmometer to investigate diurnal tear film osmolality

Recently published articles:
Here Advanced Tear Osmometer is used and referenced as a tool for measuring TEAR FILM OSMOLALITY. Both articles indicate an increase in the tear film osmolality of dry-eyed patients.These articles are available for download from their respective journal sites:

Srinivasan S, Joyce E., Jones L. Tear Osmolality and Ferning Patterns in Postmenopausal Women. Optometry and Vision Science 2007;Vol. 84, No.7: 588-592.

Nichol J., Sinnott LT. Tear Film, Contact Lens, and Patient-Related Factors Associated with Contact Lens-Related Dry Eye. Investigative Ophthalmology & Visual Science 2006;Vol. 47, No. 4: 1319-1328.