Spiral Gradient Endpoint™ (SGE™) Test

Spiral Gradient Endpoint Test for Antimicrobial Susceptibility Testing

The Spiral Gradient Endpoint (SGE) test from Spiral Biotech provides multiple uses for antimicrobial testing. SGE is highly sensitive and repeatable for minimum inhibitory concentrations (MIC) determinations by a novel patented agar dilution method. SGE produces extremely useful and precise results for the study of antimicrobial compounds and their effects on organismal growth.

• Precise MIC determinations
• Challenge 15 strains against an antimicrobial gradient
• Greater sensitivity
• User-defined libraries of microbes and antimicrobials
• Use your own compounds or standard antimicrobials
• Save user-defined stock concentrations and plate layouts
• Export to Excel
• Observe Biocidal and Biostatic interactions

Applications:
• Antimicrobial/Drug Discovery
• Drug Synergy Studies
• Antimicrobial Effectiveness
• Preservative Effectiveness
• Mutagen Screening

How it Works:
SGE uses the unique plating action of a Spiral Biotech Autoplate^TM 4000 Spiral Plater to achieve the equivalent of eight two-fold dilution plates. The volume deposited is precisely controlled and exponentially reduced as the stylus “spirals” out across the plate. Up to 15 different test strains are applied across radial lines and the MIC is computed from the measured radial location of the transition from growth to no-growth.