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Osmolality Explained
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Osmolality Equation
Osmolality Equation
Osmolality is the number of Osmols of solute particles per kilogram of pure solvent. Since most ionic species do not completely dissociate, osmolality is a unit of concentration, which takes into account the dissociative effect. Osmolality is usually expressed in mOsm/kg H20. One milliosmol (mOsm) is 10-3 osmols. The osmolality equation is:
| Osmolality = | ΦnC = | osmol |
| kg H20 |
Where:
Φ = osmotic coefficient, which accounts for the degree of molecular dissociation
n = number of particles into which a particle can dissociate
C = molal concentration of the solution
Φ = osmotic coefficient, which accounts for the degree of molecular dissociation
n = number of particles into which a particle can dissociate
C = molal concentration of the solution
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